However, one of the most important factors in determining bioavailability is the size of the molecule trying to cross the gut barrier.Ĭonsider the basic process of digestion in which large particles are broken down by enzymes, acids and muscle action into particles small enough to be absorbed through the intestinal wall. There are a host of reasons why a drug or supplement may not be readily bioavailable including the gender, age, and gut health of the person consuming the supplement. The extra time also often just moves things along and expensive supplements go straight out the other end. This extra time in the gut breaks the supplement into random fragments that no longer have the same potency as the original form. Supplements that are highly bioavailable easily slip through the gut barrier while those with low bioavailability tend to spend much more time in the gut. In fact, the effectiveness and potency of any drug, supplement or vitamin is completely dependent on its absorbability or bioavailability.īioavailability refers to how much of a consumed supplement, vitamin or prescription medication ends up entering your bloodstream in its original form. This equation is more accurately represented as nutrients absorbed equal nutrients available. But this calculation is not as simple as nutrients consumed equal nutrients available. It’s easy to assume that your body utilizes all of the nutrients and medicinal ingredients you give it.
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